Insomnitol

Natural promotion of quality sleep.

Insomnitol is a blend of botanical, nutrients, and neurotransmitter precursors designed to support quality, restful sleep. By providing nutritional support for calm brain activity, Insomnitol helps pro­mote the natural ability to fall asleep and stay asleep.

Key ingredients include botanical that support nervous system function, PharmaGABA™ (a proprietary form of GABA), L-theanine, melatonin, 5-HTP, and pyridoxal-5-phospate (activated form of vita­min B6).

Insomnitol is a formulary blend of botanicals, nutrients, neurotransmitters, and neurotransmitter precursors designed to support quality sleep and the promotion of calming brain activity. Insomnitol promotes GABAnergic and seritonergic activity, supporting the ability to get to sleep, and stay asleep. Now clinicians can attain all of the various interventions typically used in natural promotion of quality sleep in one product, improving patient convenience and compliance.

Insomnitol may:

• Serve as a sleep aid and general relaxant without causing sleep hangover

• Provide a natural sedative effect without causing drowsiness upon awakening

• Reduce generalized anxiety symptoms

• Improve pain tolerance in chronic pain syndromes, increasing the ability to sleep through the night

Supplement Facts
Serving Size: 2 capsules
Servings Per Container: 30
Amount Per Serving
% Daily Value*
Vitamin B6 (as Pyridoxal-5-Phosphate) 10 mg 500%
Valerian Root (Valeriana officinalis)(root)†[standardized to contain 0.8% valerenic acid] 400 mg*
Passion Flower (Passiflora incarnata)(aerial) [standardized to contain 3.5% flavonoids] 200 mg*
Lemon Balm (Melissa officinalis)(leaves) [standardized to contain 5% rosemarinic acid] 200 mg*
German Chamomile (Matricaria recutita)(flower) [standardized to contain 1.2% apigenin 200 mg*
Gamma Amino Butyric Acid (as PharmaGABA) 100 mg*
L-Theanine 100 mg*
5-HTP (5-Hydroxytryptophan) 100 mg*
Melatonin 3 mg*
† Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
†† Daily Value not established

Key Ingredients of Insomnitol

Insomnitol contains valerian root (Valeriana officinalis), passion flower (Passiflora incarnata), and lemon balm (Melissa officinalis), all safe nervine botanicals known for their relaxant properties and ability to reduce tension and promote sleep, without causing morning grogginess.

Valerian root has demonstrated sedative effects due to its ability to induce the release of GABA from brain tissue. It has been suggested that the passion flower and German chamomile (Matricaria recubita) constituent apigenin binds to central benzodiazepine receptors, possibly causing anxiolytic effects (anxiety reducing) without impairing memory, diminishing motor skills, or causing drowsiness upon awakening. Lemon balm has been suggested to improve calmness via the inhibitory action of GABA, similar to benzodiazepine, but without the overt side-effects of these medications. Direct stimulation of Gamma aminobutyric acid (GABA), the main calming neurotransmitter in the body, is provided with a new form of GABA known as PharmaGABA, a proprietary material naturally manufactured via a fermentation process and considered more effective than other traditional, chemically produced synthetic forms. In addition, support of calming neurotransmitter production is provided with the inclusion of L-theanine, clinically proven to reduce stress and improve the quality of sleep.

Insomnitol also includes melatonin, a multifunctional hormone whose main role lies in its involvement in the control of the circadian (day/night) biological rhythms. Melatonin mediates the body’s response to variations of natural light availability from indoor/outdoor exposure or due to seasons (winter/summer). Darkness into the eye tells the brain to make melatonin so the body can prepare for sleep mode. Its production should peak at night and it is instrumental for maintaining quality sleep patterns. Melatonin production declines significantly with age, often causing sleep difficulties associated with aging. Supplemental melatonin was shown in studies to help with falling asleep when taken about 30 minutes before the desired
sleep time. The most common dose found effective for sleep was 3mg.

5-HTP can be used in conjunction with melatonin, as a precursor to serotonin, which can further support endogenous melatonin production during the night to help with staying asleep. When using 5-HTP for enhancing serotonin and melatonin production to promote healthy mood and sleep, the addition of the synergistic nutrient pyridoxyl-5-phospate, an activated form of vitamin B6, is suggested to catalyze the conversion of 5-HTP to serotonin (5-HT).

Other ingredients:
Microcrystalline cellulose, vegetable stearate, silicon dioxide.

Suggested dosage:
Take 2 capsules, 30 to 60 minutes prior to bedtime, or as directed by your health care practitioner.

Who should take Insomnitol
Due to the inclusion of GABA, this product is not recommended for pregnant or lactating women, as well as young children, unless under the guidance of a health care practitioner.

Interactions with drug therapy
Melatonin and 5-HTP may not be suitable to administer along with SSRI and MAOI medications and corticosteroid therapy. Please discuss this with your health care provider before using Insomnitol with these medication classes.

Conditions for which melatonin is not recommended

  • Autoimmune conditions such as lupus or arthritis, because the immune stimulatory effect of melatonin may exacerbate the action of certain types of lymphocytes or B-cells involved in the pathogenic course of these diseases.
  • Immune-related cancers such as lymphoma and leukemia.
  • Pregnancy, lactation or during the time where fertility is desired.

Keep out of the reach of children. Do not use if outer seal is damaged or missing. Store in cool, dry place. Tamper resistant / double sealed.